Judging from his signature I couldn't even begin to have the same knowledge as avds but I've some personal experience with Conduit and another browser hijacker the name of which I have forgotten.
Both hijackers only went for Google Chrome presumably because that was the default browser.
I ran MSE and Malwarebytes in both standard and Safe Mode. Removed the software one of the hijackers arrived with, did a System Restore. None of these worked.
Realising Chrome was "infected" but IE was not I decided to uninstall Chrome completely. After doing this I rebooted and used IE to download and reinstall Chrome.
This solution worked immediately for the office machine which I had left running MSE and Malwarebytes for hours on the two modes.
On getting home I booted up the "infected" laptop, removed Chrome, reboot and reinstall
Both machines have been fine for two months or more.
I'm sure avds is giving good advice but five minutes spent uninstalling and reinstalling Chrome might be worth trying first. Make sure there are no unrecognised programmes installed first by looking in Control Panel