Given your location and the 'station to station' request, do I take it this will be a once or twice only journey?
If so, I would aim for directness and ease of navigation.
Which gives something like London Wall through Smithfield onto Holborn/High Holborn, keeping straight on (as much as you can) along New Oxford/Oxford Street to Marble Arch, still straight on to Bayswater Road, pulling a right just before Lancaster Gate to work your way to Sussex Gardens/Praed Street.
There are literally dozens of refinements you could make, even sticking to that basic route, so there's no right or wrong answer to your question.