Yes, Been on Omeprazole for a few years, as when they found it they gave the figure as a 1/20 chance of it developing into something more serious. Latest research suggests that the figure is something like 1/10,000 chance. I don't have any symptoms at all (they only found it because they were doing a more general investigation), but the Omeprazole is to prevent any further change in the oesophagus lining.