Saddles comfort
is an individual thing and I dare say people here will be offering you all sorts of remedies based on their own experiences. So, from my own experience
, if all else has failed - try a Brooks. The fundamental difference between a Brooks and all others is that it isn't relying on cushioning for comfort - there is none. Knock on a Brooks saddle and it's like knocking on a door. It's rock hard. Put all your weight on a Brooks saddle though and it will flex. The comfort is in the flex and for that flex to work you need thick leather and a quality leather, and that comes at a price. But if it works for you, you need never buy another saddle again. Looked after properly it will last literally decades. If it doesn't work for you then sell it - you will always, always get a decent resale price for it.
Some people swear by the B17 which is their cheapest, though I think it looks a tad old fashioned. Better looking and more modern are the Professional and the Swift. I have a Swift on my Cannondale road bike which has been there for only a few months and I have had the bike 10 years. The old saddles - and there were 4 of them, would be ok for around 25-30 miles. After that - agony.! Once I put the Brooks on, my first run was 60 miles in instant and supreme comfort. And I haven't looked back. A friend of mine has just done the same and put one on his Cube carbon bike. They will fit on anything, look the part and weigh around the weight of a couple of tomatoes more than the one you take off.
Decent website
here by the way, for the range.