Colesterol and statins

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Dogtrousers

Kilometre nibbler
Think it's pretty standard to prescribe a statin for anyone who's had a TIA irrespective of their cholesterol levels.
Statins do more than just lower cholesterol. They can also stabilise existing plaques, and have a protective effect on the arterial lining, etc.

After my TIA I had a chat with the consultant about statins, and without going into detail, this was broadly the thrust of what he said. Not a million miles off anyway.
 

T4tomo

Legendary Member
Its a whole can of worms, cholesterol levels.

The overall cholesterol number is not the important figure, its the HDL to LDL ratio that more important. Below 3.5 is excellent, below 5 is ok.

Also the triglycerides figure is important, it indicates how much free lipids(fats) are circulating around your blood stream, less than mmol/L < 2.3 is fine.

The key ration is Serum Cholesterol (so called Total Cholesterol ) / HDL Cholesterol (not LDL/HDL) and yes Below 3.5 is excellent, below 5 is ok.

Your HDL (so called good cholesterol) level should be above 1.0 for men and 1.2 for women.
 

yello

back and brave
Location
France
Your HDL (so called good cholesterol) level should be above 1.0 for men and 1.2 for women.

Looks like they say 1.45 mmol/L for men here in France. Mine's 1.34. That's according to my last results in 2023. My total ratio was 3.8. Triglycerides were 0.83. Looks good to me.
 

bobzmyunkle

Über Member
Interesting to play about with it to see what drives the numbers
Age - don't get old.
I did look into cholesterol on the good old interweb. What a rabbit hole that turned out to be. Anyhow last time I had mine checked my 'good' cholesterol was reassuringly high.
Retired now, the corporate world no longer cares about my health, no routine checks. I'll believe the last figures I got for a while longer.
 

CXRAndy

Guru
Location
Lincs
The key ration is Serum Cholesterol (so called Total Cholesterol ) / HDL Cholesterol (not LDL/HDL) and yes Below 3.5 is excellent, below 5 is ok.

Your HDL (so called good cholesterol) level should be above 1.0 for men and 1.2 for women.

My good cholesterol HDL is 1.9
 

CXRAndy

Guru
Location
Lincs
Interesting comparisons... my total ratio hovers around 3.0 - 3.1, triglycerides about 0.7, yet I get lectured by the cardiologist to do more to reduce it.

If you don't have any other complications then you're probably good to go. High blood pressure, cardiac and arterial issues it could be different.
 
Bump.

But of eye opener for me. Lipoprotein A blood check this week after a recent heart attack.

Mine came back as 147.3 nmol/L which puts me in the high risk group. It's genetic and as of right now there isn't much that will shift that number downwards. I was most likely born with 147.3 and will most likely die with 147.3.

Interesting though that when you are told you have genetic high cholesterol - they don't mean you have geneticly high LDL - they are talking about high lipoprotein a - but it isn't often measured as there in no treatment for it.

High lipoprotein a is a risk in its own right. Even if your other cholesterol scores are good (which they can be even high lip a) you are still at increased risk .

Have a nice afternoon all.
 
Are you sure? I have genetic high LDL and normal Lpa.

To be honest no !

I have low LDL even before statins. They couldn't understand where all the plaque in my arteries was coming from. GP said maybe it's genetic - so I asked for tests to prove disprove/prove genetic cholesterol levels - LPA was the test I was given.
 

mjr

Comfy armchair to one person & a plank to the next
To be honest no !

I have low LDL even before statins. They couldn't understand where all the plaque in my arteries was coming from. GP said maybe it's genetic - so I asked for tests to prove disprove/prove genetic cholesterol levels - LPA was the test I was given.
Interesting. I think I was LpA tested because the treatment differs if it's high. I thought the most reliable way to confirm genetic high cholesterol is gene profiling and look for known causes, which seems to take a long time to get done, and of course can only confirm it, but not disprove it because experts think not all possible genetic causes have been found yet.

Most of the time, the Broome criteria are a good enough guess.
 
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