My audax-y bike has a campag 'race triple' 30 - 42 - 52 and campag's 13 - 28 cassette
Never had a problem adjusting the mechs to work in harmony with one another.
Never (yet) had a hill I've had to walk, albeit I might be going up slower than if I was walking.
Some roadies point and laugh at the cage length on the rear mech and claim it is ugly. Woe betide them if I pass them walking on a climb.
Without luggage riding solo I rarely if ever use the small ring these days in day-to-day use since my leg strength and fitness are such I don't need it. (But it is darned useful when commuting on 'recovery ride' days to get up the 15% hills)
With luggage, think fast credit card touring, a couple of panniers say, the small ring is useful when one is tired at the end of the day and there is one more big hill, or even mountain, to get over.
When riding in a group the small ring is, basically, more sociable. It enables me to ride at a pace that others can manage, this is a good thing if say you're riding up a mountain pass with a weaker rider.