supposedly. i find some work better than others, and depends on the tyres. my crank brothers mini pump just won't get my tub tyres up to any great pressure, but is fine with vittoria clinchers, whereas an old mini pump works fine with both, but not as good as the crank brothers' one with the clinchers. as none of my bikes are super lightweight, and i have the frame pump (which works well with everything), i prefer to use that.
if you're starting from a position of having neither, take your bike and try them out. or, alternatively, start a "which pump for such and such tyres" thread.