The other way to...er...tackle it is to go for the cut away solution. Selle SMP saddles have been mentioned above but there are also ISM saddles, one of which I'm currently trying out, that follow the same principle of removing the central cause of the circulatory blockage.
The cut away is basically a more extreme version of traditional saddle shapes which dip in the front-back direction. It all depends how little support you want there and whether the edges of the cut away suit you.
I think of the traditional saddle as shaped like a Brooks. I meant saddles with a central cut away, which has a gap where a Brooks presses. From my experience, the saddle tilt part of it is important for riding comfort but the numbness can come from slight central pressure on the perineum and whatever veins run along there. Cut aways take that out of the equation. Though, of course, the question whether it suits you is always crucial.
level or slightly down is the way forward - if your shoulders and neck can take the extra strain tilt it even further down!
I find that even very subtle adjustments of the saddle angle and setback can make a BIG difference to my comfort. Once the offending part of the saddle is safely lowered away from where it is causing a problem then not much would be gained by lowering it further, and I would definitely get shoulder and neck problems with a steeper saddle angle which would tend to make me slip forwards.
I think of a saddle as shaped like a saddle surface https://en.m.wikipedia.org/wiki/Saddle_surface
They sell that in my local Tesco, had me in childish stitches one night!
