I bought a portable unit on an offer back in 2011. It worked ok, but it was noisy to run. The pump sent vibrations through the floor, I couldn't sleep with it on but it was good to run for a couple of hours before bed. Better/more modern/more expensive units are probably quieter these days.
The other issue was the vent pipe. It needs to go out of the window, obviously, or you're just heating up the room. Also the rest of the window should be sealed round the vent pipe, or warm air is just coming back in. It came with a kit for sash windows but ours are full openers. I tried to rig something up with cardboard and gaffer tape but way too much of a faff and looked terrible. So ended up just sticking the pipe out of the open window; not very efficient. The vent pipe was quite stiff and awkward to manage, would be better to set it up for a longer time. I sold it a couple of years later, not worth the trouble for the 3 or 4 days a year it made sense to set it up.
They are semi portable at best. Yes you can roll them round on castors but unless you've got a suitable vent kit in every room you use it in, it's not worth it.
The permanent units like Drago's are the way to go and I'm considering one for our loft.