I havent done anyhting different to usual, although I am a little heavier than I was 3 years ago..but not much. I have noticed more rubbish in the roads ...glass and grit and flint chippings etc...but doubt that is enough to warrant such a change...maybe it's jus tthe way it goes...weeks without a puncture then 5 in a week
Fair dos, I've never had a bad spell like that but I know my mind will turn in the same sort of directions as yours when it happens. I've already given it some thought due to taking up offroading, but still on tubes at present. Some of my ideas:-
Tyres - puncture resistance v comfort/speed - if it's for time constrained destination imperative type journeys, as in commuting, then I'd go M+ but only if I could use 700x32 or bigger. I didn't like them in 700x28, much harsher, and can only imagine anything smaller to be worse in that respect. Originally I ran Slime tubes and M+ tyres, scared of punctures. Gradually moved on, ditching the Slimes first then the M+ for anything but commuting, then even for commuting. I think a rash of punctures would see me back on the M+.
Tubes - the Slime ones, and variants, are pricey and not always effective - if you have a removable core you can put 'sealant' into any tube - that could be your best low cost solution. There are tougher tubes around but I'm wary of that as an idea. If something has penetrated the tyre casing a tougher tube may withstand it...but for how long?
Tubeless - going tubeless is an option though trickier and more restrictive with higher pressure narrower road tyres. If you're running bigger tyres then easier and, either way, you can still carry spare tubes just in case. I'd guess the big benefit with tubeless would be no tube to re-puncture. BUT I HAVEN'T TRIED A TUBELESS SYSTEM so this is all based on internet chatter. Of my two local bike shops I use one recommends it highly and the other says avoid like the plague
I suppose eventually tyres will all be tubeless and without sealant and we'll just carry innertubes for emergencies.