If you're putting your foot down a lot, I'd say no, personally. (Incindentally, the clip out is fine, it's the clip in that's different, and I think trickier than SPD).
My commute has a train journey in the middle, so road cleats are a non-starter for me anyway there because of the amount of walking - it would wreck road cleats. Most weeks, I have 5 rides on SPD, 1 ride on SPD-SL, so I may be a bad example, but personally, I think the clip in is problematic enough on SPD-SL that I'd not use it on short-ish urban rides - I'd also be worried about the wear on cleats on my clip out foot at all the stops, but that may be an unreasonable worry.