Yes - they will be lighter/stiffer & accelerate faster.
300g saving is a big benefit when you hit the climbs.
How much do you want to spend ?
Now I don't know if this is what is called bumping (I don't know what that is) but... it sounds naughty.
I have just photographed my unused/as new Ritchey WCS Zeta wheel set.
They were taken off my brand new but 2012 model bike (bought it Sept 2013) & never ridden.
They were rolled from Tweeks shop door to my car boot.
At 1595g the P-SL 0 wheels are close to the Ritchey's - 1545g & Titanium Q.R's for that model year.
Late 2012 they went up in weight to 1623g & in Oct 13 were replaced by the Zeta 2 @ 1450g weight.
I am going to put them up on the classifieds here for a few days before they go to
ebay & will include the Vittoria Rubino Pro tyres & tubes they came with (also never used).
If this sounds like an option PM me & I will give detailed spec.
Will post or email photos too.
The Giants you have been offered are plenty good enough if the price is right.
Be Lucky.
Centurion.