Interleukin-6 some questions answered

[Zoof]

Stop worrying guys we are singing from the same hymn sheet. You have given my/your enemy a name. Now lots of pieces of the puzzle on training, just fit into place.

Do you think that IL6 has to be a part of a survival mechanism?

 

[Arsen Gere]

Becs,
I think the telegraph article is rather poor. It lacks balance and is weighted to build headline. It would have been less dramatic if it had quoted Timmons as saying "exercise training is, on average, beneficial for metabolic and cardiovascular health, for the majority of people", as stated here. But I take your point regarding genetics.

 

[Becs]

Becs,
I think the telegraph article is rather poor. It lacks balance and is weighted to build headline. It would have been less dramatic if it had quoted Timmons as saying "exercise training is, on average, beneficial for metabolic and cardiovascular health, for the majority of people", as stated here. But I take your point regarding genetics.

I know it's not great but I didn't think your average CC reader would want to read/understand the full J appl phys paper!

IL-6 is implicated in many biological processes but it never works alone. Cytokines work in a very complicated web of positive and negative feedback loops with a large amount of crossover between the 1000s of cytokines that we currently know about. It is interesting that IL-6 is correlated to so many aspects of training, but I'm sure there's a whole lot more to it than that!

 

[Wobblers]

http://www.telegraph...by-jogging.html

I think I am a low responder!

That Telegraph article is clearly written by someone who doesn't know their arse from their VO2 max!

It's well known that some people simply don't respond to exercise by getting fitter - as defined (badly!) in the article as an increase in oxygen uptake. Those people will find that, no matter how much they exercise, they won't see any improvements in speed. That doesn't mean to say it's not doing them any good. It's been shown that they still see a decrease in mortality and diabetes risk. To suggest otherwise is just sensationalist bollocks. Sadly, it's quite typical of the standard of reporting of science...

 

[Becs]

That Telegraph article is clearly written by someone who doesn't know their arse from their VO2 max!

It's well known that some people simply don't respond to exercise by getting fitter - as defined (badly!) in the article as an increase in oxygen uptake. Those people will find that, no matter how much they exercise, they won't see any improvements in speed. That doesn't mean to say it's not doing them any good. It's been shown that they still see a decrease in mortality and diabetes risk. To suggest otherwise is just sensationalist bollocks. Sadly, it's quite typical of the standard of reporting of science...

yep, sadly. The research is excellent, the article is not - I merely linked to it as the first lay-person friendly mention of the study in question after some light googling (i.e. I couldn't be arsed to read it all). The original paper is in the other link and is quite handily "free full text" if anyone is interested. I just hope horizon do a better job than the Telegraph!