Thanks
I am not too concerned about tyre width. In fact I will most defiantly err toward road profiles. One of the things I noticed when I went to the hybrid was that for my style of riding the advantages of roadish tyres far outweighed the loss of the advantage of wider or knobblier ones. If I am slogging up a boulder strewn, dried up stream bed with full camping kit, I am likely to be pushing anyway. The times I miss the knobblies is in deep mud, which can soon stop even the most aggressive tyre or damp grassy slopes. Both of which I do find a lot of but by avoiding the first and lowering tyre pressures for the second I can cope with.
I would like to use my old mtb Machine Tech hubs which are cnc'ed from solid and the size of a pop can. Disadvantage is that the freewheel is so loud that should I stop peddling they will flush all wildlife as I approach. Good for clearing towpaths of peds though.

Initially due to the cost of a custom build, I might have to settle for a strong set of second hand road wheels. I am quite confident that the rear triangle of the frame, a Zaskar LE, is capable of coping with the required flex. I suspect it used to move by the required 5mm every time I used my old Maguras in anger. I don't know of a stronger frame. I would use my old Maguras or cantis on an adaptor plate.
I am a bit confused about gearing though. I need new rings and cassette so will need to reach a decision on these. I have options of an XTR short cage rear mech which I would prefer to use. I was happy with the gear spread it covered with 16" wheels for primarily off road use and like the crisper changes of a short cage. I am not sure though that it will be as effective with 700's for the amount of good surface riding I expect. I do have the option of a long cage SRAM which will widen the available range and might be the way to go.
Any idea on the effect on gearing of changing from 16" to 700c? I know there are tables but they give me a headache. Just an idea of the %age change would do.
As you say CA, well built 700's are surprisingly strong. It should be remembered that the whole development of 16" wheels for mtb's was primarily driven by tyre availability in the States in the 70's rather than any intrinsic strength.