Viagra; does it work physically or psychologically?

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PaulB

Legendary Member
Location
Colne
Does it work at all?

Well over the last two weeks, we have conducted a double-blind, placebo-controlled trial and this is what we found.

I've always had my doubts about most pharmaceuticals when outrageous claims are made for them by the people who make big profits. I've always thought people who take Viagra recreationally are foolish as well. On the one hand, if Viagra does work and you don't NEED it but take it for 'fun', if the day ever comes when you DO need it, it won't work; all the receptors will be blunted. But does it work psychologically? By which I mean 'ooh, I've taken that little blue lozenge, better fire up the jets'?

So what we did was this; being medical-minded and having taken part in medical trials before, we double-blinded it to prevent operator bias. We obtained one 50mg Viagra from an impeccable source and five identical placebo tablets. Mrs. Paul B took the Viagra, crushed it between two spoons and poured the contents into an envelope. She had taken a felt-tip pen and made a tiny mark in the innermost recesses of the envelope to determine this was the Viagra. She then took the five other tablets, crushed them and placed each one inside a separate envelope, no marks made. All envelopes sealed, I was then summoned to shuffle all the envelopes and write on the outside of each one Monday 1, Tuesday 1, Wednesday 1 and Monday 2, Tuesday 2, Wednesday 2. The contents of each envelope would be poured into a glass of water at 6pm on the appropriate day (week 1, week 2). This also removed the weekend's inevitable relaxation from the equation.

Having consumed each pill, I was required to keep a diary recording any, to express this in bald medical terms, 'betwitchering of the nether-breech region' on the corresponding day, if you know what I mean! On the Thursday of week two, we would then rip open the envelopes to discover which envelope mark revealed the day the actual Viagra was consumed.

Now I'm not going in to specific details but let's just say that this small test revealed to us that Viagra doesn't do what is being claimed for it. It transpired that the actual real McCoy was consumed on Tuesday of week 1 and comparing 'events' showed absolutely no difference between that day and the other days.

So there's my findings.
 

Allirog

Active Member
I think you need to be in a 'horny' frame of mind when you take the pill; the ingredients probably assist the blood flow to the floppy trouser snake but don't actually make you feel randy.
 
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PaulB

PaulB

Legendary Member
Location
Colne
I think you need to be in a 'horny' frame of mind when you take the pill; the ingredients probably assist the blood flow to the floppy trouser snake but don't actually make you feel randy.

If you're in a 'horny frame of mind' then it works psychologically, surely?
 
I used to give sildenafil (Viagra) to horses with pneumonia to treat their pulmonary hypertension - you can imagine the looks I got ordering horse doses of viagra from the pharmacy! Incidentally it works better if you combine it with nitrous oxide (laughing gas).

It has a very definite physiological action (it is a phosphodiesterase inhibitor) and is used to dilate the vessels in the lungs in times of pulmonary hypertension such as severe pneumonia, left-sided heart failure, high altitude sickness and thrombolembolic disease. . . . . . it just so happens that it dilates the vessels in your man parts too!
 
Viagra was not developed for the current application. It was developed as a heart drug. It was only as a result of lots of the trial patients not on the placebo reporting a much appreciated side effect that Viagra as we know it was born. There is no reason for any of those patients to have had a placebo effect reaction of the type they did - it was about as blind a blind trial as you can get.

So I would put it down to your experiment being flawed.
 

007fair

Senior Member
Location
Glasgow Brr ..
no expert but
I don't think the pill will make you randy
Intended use was for people who felt randy but could not perform

Doesnt sound like you are good test cases
 
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PaulB

PaulB

Legendary Member
Location
Colne
It was only as a result of lots of the trial patients not on the placebo reporting a much appreciated side effect that Viagra as we know it was born.

And having the hell promoted out of it by Pfizer in order to make a MASSIVE profit. In my own placebo-controlled, double-blind trial, it doesn't work.
 

Canrider

Guru
And having the hell promoted out of it by Pfizer in order to make a MASSIVE profit. In my own placebo-controlled, double-blind trial, it doesn't work.
As has been pointed out to you, your trial was not measuring what you thought you were measuring.

Let me rephrase that: your trial has confirmed what was already known, that is, that taking sildenafil in the absence of ED yields little or no effect beyond that of a placebo.
 
And having the hell promoted out of it by Pfizer in order to make a MASSIVE profit. In my own placebo-controlled, double-blind trial, it doesn't work.

Having passed rigorous regulatory hurdles requiring them to show efficacy for the claimed application.

Of course they are promoting the hell out of it now they've got it but the whole way it originated shows it does work and either your trial was faulty or your problem is not one that it addresses. It only deals with certain physical causes from restricted blood flow and won't help if the problem is psychological (other than through placebo effect) or neurological for example.

Are you using the real McCoy or did you buy it over the internet?
 
Let me rephrase that: your trial has confirmed what was already known, that is, that taking sildenafil in the absence of ED yields little or no effect beyond that of a placebo.

I does have benefits for "normal" men in both treating premature ejaculation and in reducing down time.
See for example this paper But as the paper concludes its use in normal men to reduce down time is not ethical.
 

Melonfish

Evil Genius in training.
Location
Warrington, UK
isn't viagra just a specific vasodialator? i believe a few athletes take this in the belief it helps blood flow to the muscles etc.
can't imagine running the 100m packing wood mind, especially in those lycra shorts they wear...
pete
 
isn't viagra just a specific vasodialator? i believe a few athletes take this in the belief it helps blood flow to the muscles etc.
can't imagine running the 100m packing wood mind, especially in those lycra shorts they wear...
pete

Yebbut think of the advantage in the three legged race ;)
 
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