As far as I know the wheels are normal wheels - unless the motor is in the hub of course.
Actually the tyres are just normal tyres as well
I wouldn't use very lightweight wheels but any normal commuter bike or mountain bike wheels should be OK
I know the bikes are heavier - but at the end of the day the main weight they have to cope with is ME - by a long way!!!
Just the weld point on the wheel rim. There are just bigger touring tyres for ebikes, anything with a decent sizee, 35mm or more is plenty. Ebike weighs maybe 8kg more than standard road bike. so not vast difference.