The only issue I've ever had running 25c tyres was cornering at speed with some heavy wire beaded gatorskins, the extra weight of the tyres seemed to make cornering hard work, requiring more effort and weight shifting to make the bike turn into the corners in a way I was comfortable with, this problem went away with lighter tyres at 24c, not sure if the size of the tyre was the issue but may be a combination of factors.
There may still be some 24c continental grand prix tyres available, I found these to be almost perfect in terms of handling, comfort and weight.