I haven't tried units from another manufacturers than Garmin so this is not an unbiased opinion.
I find the Edge Explore 2 excellent. The UI is much improved from the 530 I had, however it can still be unintuitive at times. Generally though if you spend some time going through the menus and trying different options it becomes clearer. It's also worth playing with the device in your hand as if you're on a ride to get used to how to do things. For example knowing how to switch map modes into pan and zoom will save you time and swearing if roads are closed but the unit still insists on trying to route you down them.
Operating it on the bike though is pretty good. Bottom right button to start and stop/pause ride. Swipe down from the top to access sensors, e.g turn on and off lights or change modes, and to access stored routes. Swipe left and right to change between data screens (or leave it on map).
I like to have speed on screen at all times, so have added it as a field to the map screen. If the screen is on another data screen it will swap to a simple map screen when approaching a turn, then switch back to the original screen.
The touch screen is obviously challenging in gloves unless you have touch screen compatible ones. My winter gloves seem to work ok on it. Above about 8-9C ambient I wear fingerless mitts so it's fine.
Integration is good with the Garmin Connect app. Routes planned on Connect can be sent to the device with one click, other software can be integrated easily via Connect. I mostly plan routes on Cycle.travel and send it Connect one click.