Snake Pass ascent from Glossop, follow the Snake and turn off onto the Strines road and follow that to the Stocksbridge bypass which means you can do the 25% climb at Ewden Bank as well as plenty of other digs on the way. The only problem after that is the Stocksbridge Bypass/Woodhead traffic, so I'd turn around after the climb and go back on the Strines road the other way, which means you also get the 18% short sharp climb at the other side of Ewden bank and a couple more on the way back to the Snake, as well as the long but steady E-W snake ascent.
Or, go right at the Ladybower traffic lights, follow the road to Bamford and turn left up the surprise climb to Fox House, turn right just before there and go back down to Grindleford, turn right over the bridge at the bottom and head back to Bamford where you turn right back to the Ladybower. You could do it the other way around too and climb from Grindleford then descend the surprise.