rb58
Enigma
- Location
- Bexley, Kent
Errr, I think you'll find what you spotted was the unimpressive surrounding wall, not the great big castle behind it........
FNRttC Friday Night Ride to the Coast 21st March - Burnham-on-Crouch via Junction 31
- Thread starter dellzeqq
- Start date
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Errr, I think you'll find what you spotted was the unimpressive surrounding wall, not the great big castle behind it........
martint235
Dog on a bike
- Location
- Welling
I spotted that on the way back!!!!Errr, I think you'll find what you spotted was the unimpressive surrounding wall, not the great big castle behind it........
Fab Foodie
hanging-on in quiet desperation ...
- Location
- Kirton, Devon.
The previous ride ...
surprisingly little has changed. Although there are more of us now.The previous ride ...
Fab Foodie
hanging-on in quiet desperation ...
- Location
- Kirton, Devon.
Oo-eck .... explains a lot though ....
http://www.bbc.co.uk/news/health-26630647
Lost sleep leads to loss of brain cells, study suggests
COMMENTS (167)
By Helen BriggsBBC News
Sleep loss is bad for mood and mental processing
Continue reading the main story
Related Stories
Sleep loss may be more serious than previously thought, causing a permanent loss of brain cells, research suggests.
In mice, prolonged lack of sleep led to 25% of certain brain cells dying, according to a study in The Journal of Neuroscience.
If the same is true in humans, it may be futile to try to catch up on missed sleep, say US scientists.
They think it may one day be possible to develop a drug to protect the brain from the side-effects of lost sleep.
The study, published in The Journal of Neuroscience, looked at lab mice that were kept awake to replicate the kind of sleep loss common in modern life, through night shifts or long hours in the office.
We now have evidence that sleep loss can lead to irreversible injury”
Prof Sigrid VeaseyUniversity of Pennsylvania School of Medicine
A team at the University of Pennsylvania School of Medicine studied certain brain cells which are involved in keeping the brain alert.
After several days of sleep patterns similar to those followed by night workers - three days of night shifts with only four to five hours sleep in 24 hours - the mice lost 25% of the brain cells, in part of the brain stem.
The researchers say this is the first evidence that sleep loss can lead to a loss of brain cells.
But they add that more work needs to be done to find out if people who miss out on sleep might also be at risk of permanent damage.
Prof Sigrid Veasey of the Center for Sleep and Circadian Neurobiology, told BBC News: "We now have evidence that sleep loss can lead to irreversible injury.
"This might be in a simple animal but this suggests to us that we are going to have to look very carefully in humans."
She said the next step was to examine the brains of shift workers after death for evidence of any loss of brain cells.
Shift work may have permanent health implications
In the long-term, they think it might be possible to develop a medicine that protects brain cells, by boosting a natural chemical involved in sleep recovery.
Prof Hugh Piggins of the University of Manchester said the experiment indicated in a mouse model of sleep deprivation what might go wrong in the human brain.
"The authors draw parallels with night shift work in humans and suggest how chronic sleep deprivation could adversely affect not only our physical, but also our mental health," he said.
"This possibility will need to be tested by a lot more research. Nonetheless, it is consistent with many recent reports of importance of circadian clocks and sleep cycles for optimal well-being. "
http://www.bbc.co.uk/news/health-26630647
Lost sleep leads to loss of brain cells, study suggests
COMMENTS (167)
By Helen BriggsBBC News
Sleep loss is bad for mood and mental processing
Continue reading the main story
Related Stories
Sleep loss may be more serious than previously thought, causing a permanent loss of brain cells, research suggests.
In mice, prolonged lack of sleep led to 25% of certain brain cells dying, according to a study in The Journal of Neuroscience.
If the same is true in humans, it may be futile to try to catch up on missed sleep, say US scientists.
They think it may one day be possible to develop a drug to protect the brain from the side-effects of lost sleep.
The study, published in The Journal of Neuroscience, looked at lab mice that were kept awake to replicate the kind of sleep loss common in modern life, through night shifts or long hours in the office.
We now have evidence that sleep loss can lead to irreversible injury”
Prof Sigrid VeaseyUniversity of Pennsylvania School of Medicine
A team at the University of Pennsylvania School of Medicine studied certain brain cells which are involved in keeping the brain alert.
After several days of sleep patterns similar to those followed by night workers - three days of night shifts with only four to five hours sleep in 24 hours - the mice lost 25% of the brain cells, in part of the brain stem.
The researchers say this is the first evidence that sleep loss can lead to a loss of brain cells.
But they add that more work needs to be done to find out if people who miss out on sleep might also be at risk of permanent damage.
Prof Sigrid Veasey of the Center for Sleep and Circadian Neurobiology, told BBC News: "We now have evidence that sleep loss can lead to irreversible injury.
"This might be in a simple animal but this suggests to us that we are going to have to look very carefully in humans."
She said the next step was to examine the brains of shift workers after death for evidence of any loss of brain cells.
Shift work may have permanent health implications
In the long-term, they think it might be possible to develop a medicine that protects brain cells, by boosting a natural chemical involved in sleep recovery.
Prof Hugh Piggins of the University of Manchester said the experiment indicated in a mouse model of sleep deprivation what might go wrong in the human brain.
"The authors draw parallels with night shift work in humans and suggest how chronic sleep deprivation could adversely affect not only our physical, but also our mental health," he said.
"This possibility will need to be tested by a lot more research. Nonetheless, it is consistent with many recent reports of importance of circadian clocks and sleep cycles for optimal well-being. "
rb58
Enigma
- Location
- Bexley, Kent
Well, I'm still in.
Fab Foodie
hanging-on in quiet desperation ...
- Location
- Kirton, Devon.
... well my cycle is perfectly optimised for my well-being ....
Fab Foodie
hanging-on in quiet desperation ...
- Location
- Kirton, Devon.
Well I just received my weather update from dellzeqq ... and I'm sorry, it's my fault, I'm a bad omen.
I've only participated in 1 FNRttC, in the summer, genteel to Brighton ... it pi55ed down from about Coulsden all the way to Brighton where it blew a gale the other side of Ditchling. So mighty was this down-pouring which continued after breakfast that even ianrauk balked at riding home lest his beloved bicycle dissolved in the torrent. I rode back to London alone ... ashamed.
And now once again, torrents are forecast in the small hours, I thought I should cancel my participation to save you all from sodden-ness, from watery misery, from a moist breakfast, but then again I thought ... bu99er-em ... I'm going cycling, Burnham or bust!
I've only participated in 1 FNRttC, in the summer, genteel to Brighton ... it pi55ed down from about Coulsden all the way to Brighton where it blew a gale the other side of Ditchling. So mighty was this down-pouring which continued after breakfast that even ianrauk balked at riding home lest his beloved bicycle dissolved in the torrent. I rode back to London alone ... ashamed.
And now once again, torrents are forecast in the small hours, I thought I should cancel my participation to save you all from sodden-ness, from watery misery, from a moist breakfast, but then again I thought ... bu99er-em ... I'm going cycling, Burnham or bust!
velovoice
Veteran
- Location
- Between the City and the Sea
Only 1? Then you're not responsible for all the other Epic Wet Rides. It'll be good to see you.
I've taken dellzeqq's route, and converted it to a GPSies track, from which you can download GPX and so forth. As ever, the normal rules apply, so the route may change at any time, with no warning, this is for guidance only.
First Half (up to the Dartford services)
Second Half
First Half (up to the Dartford services)
Second Half
Fab Foodie
hanging-on in quiet desperation ...
- Location
- Kirton, Devon.
See you tomorrow 
martint235
Dog on a bike
- Location
- Welling
Very rough and ready return to Dartford Crossing
Not quite the route I have.
Mines a bit more direct, south at Wickford all the way to Pitsea and pick up the normal route to Dartford and no Fenn Lane and Ockenden.
Edit: and dropping off @nigelt at Mile 28 for the Brentwood Road to Tilbury Ferry
Last edited:
martint235
Dog on a bike
- Location
- Welling
Okey dokey. Mine is just a backup in case I end up on my own for any reason.
