I Michelin Carbon Krylions (front) and Bontrager Race X Lite Hardcase (rear) on my riding trip last summer, when I rode from London to Nimes (and then the Med). It's not a bad combination.
At the moment I've switched to using the Krylions at the back and grippier Continental 4000s at the front.
No punctures through the entire trip (but had about 4 in succession when I came home so changed to a new set).
I took my single speed (I'm not generally confident enough to ride fixie) up the Ventoux. It was a real slog but still managed it in just over 2hrs.
By the way the ride down was very hairy...windy and fast!
Also, I'll take a geared bike next time

95% of the time the 1 gear was fine but on the odd occasion (climbs) it was quite hard.
A few pics here:
http://picasaweb.google.co.uk/mootaineer/LondonToMediterraneanSep2007